Clinical Services

Gastrointestinal Pathology

BioVantra offers an extensive array of anatomic pathology and molecular-based testing services specifically designed to provide gastroenterologists with information to better manage cancer and other chronic diseases. We understand the importance of accurate, timely diagnostic test results and actionable healthcare information. Our commitment to these values helps ensure superior patient care and increased client satisfaction.

The following highlights our gastrointestinal pathology test offerings:

Histology

  • Esophagus, stomach, small bowel, large bowel, and liver biopsy
  • Microwave tissue processing to minimize disruption of cellular architecture
  • Consultation and 2nd opinion
  • Special stains (Group I - Microorganisms; Group II - Cellular structures)
    • Alcian blue/PAS stains on esophageal, gastric, and duodenal biopsies
    • Comprehensive staining panel for liver biopsies
  • Immunohistochemistry
    • CD117 and H. pylori

Cytology

  • Brushings
  • Fine needle aspirations

Specialized Testing

Biomarker Analysis

  • Barrett’s BioStrat™ Assay
    • A molecular-based assay that provides valuable clinical indication of Barrett's associated neoplasia that is more specific than conventional surveillance methods alone. The assay consists of directly labeled fluorescent DNA probes that can be applied to esophageal cytology brushing specimens collected during endoscopy.
    • Provides information on DNA alterations relating to the detection of Barrett's associated neoplasia and the differentiation of low-grade dysplasia from high-grade dysplasia/adenocarcinoma.
  • DNA ploidy analysis
  • FISH

    • Chromosome 7; EGFR gene (7p12)
    • Chromosome 8; C-MYC gene (8q24)
    • Chromosome 9; p16 gene (9p21)
    • Chromosome 17; p53 gene (17p13.1); Her-2/neu gene (17q11.2)
    • Chromosome Y
  • Quantitative Immunohistochemistry
    •  ß-catenin, Cox-2, cyclin D1, EGFR, HER-2/neu, Ki-67, PTEN, p16, p21, p27, p53, TOPO1, TS
    • Microsatellite instability testing
      • Mismatch repair genes: MLH1, MSH2, MSH6, PMS2
    • EGFR pharmDx™
      • Detection of EGFR expression in metastatic colorectal cancer to aid in the identification of patients eligible for treatment with cetuximab (Erbitux™) or panitumumab (Vectibix™).

Ordering

Please contact BioVantra Client Support Center at (866) 627-8221 to arrange for urology testing. Our experienced Client Support Team can assist with:

  • Gastroenterology Requisition
  • Sample requirements
  • Logistics and specimen transportation
  • Testing methodology
  • Report delivery, status or interpretation
  • Expert oncology and pathology consultations
  • Requests for BioVantra literature and scientific references

Sample Reports

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